After years of being sheltered from the human world, the Turtle brothers set out to win the hearts of New Yorkers and be accepted as normal teenagers through heroic acts. Their new friend April O`Neil helps them take on a mysterious crime syndicate, but they soon get in over their heads when an army of mutants is unleashed upon them. The film stars Micah Abbey, Shamon Brown Jr., Nicolas Cantu, and Brady Noon in the lead voice roles. The ensemble voice cast also includes Ayo Edebiri, Maya Rudolph, John Cena, Rogen, Rose Byrne, Natasia Demetriou, Giancarlo Esposito, Jackie Chan, Ice Cube, Paul Rudd, Post Malone, and Hannibal Buress. In the film, the Turtles go on a hunt for a mysterious crime syndicate, but trouble arises when an army of mutants is unleashed upon them.